Speech metrics in multiple sclerosis

Objective measurement of speech has shown promising results to monitor disease state in Multiple Sclerosis. We describe the relationship between disease severity and speech metrics, through perceptual (listener based) and objective acoustic analysis. We also looked at deviations of acoustic metrics in people with no perceivable dysarthria.

Participants included 119 people with MS and 22 Healthy controls.

Take home points:
· In multiple sclerosis, computer-based speech metrics correlate with neurological disability in people without dysarthria.
· Acoustic analysis of speech differentiated between groups of mild, moderate and severe neurological disability
· Acoustic analysis of speech correlated with quality of life, white matter atrophy and whole brain lesion load.

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