Redenlab are glad to be supporting Larimar Therapeutics Inc. Phase 1 SAD clinical trial is a double-blind, placebo-controlled, randomized clinical trial to assess the safety of subcutaneously administered CTI-1601 versus placebo in adult subjects with Friedreich Ataxia.
Outcome measurement tools for communication, voice and speech intelligibility in the ICU and their clinimetric properties: A systematic review
Purpose To identify outcome measurement tools used to evaluate communication, voice and speech intelligibility in the mechanically ventilated ICU population. Secondly, to evaluate, synthesise and compare the clinimetric properties of the tools identified. Materials and…
Decision making biases in the allied health professions: A systematic scoping review
Abstract Objectives Cognitive and other biases can influence the quality of healthcare decision making. While substantial research has explored how biases can lead to diagnostic or other errors in medicine, fewer studies have examined how…
Instrumental swallowing assessment in adults in residential aged care homes: A scoping review
Objectives To systematically describe evidence on the use of instrumental swallowing assessment for residents of aged care homes. Design Scoping review using the Joanna Briggs Institute methodology for scoping reviews. Setting and Participants Published peer-reviewed…
Acoustic speech analytics are predictive of cerebellar dysfunction in multiple sclerosis
Speech production relies on motor control and cognitive processing and is linked to cerebellar function. In diseases where the cerebellum is impaired, such as multiple sclerosis (MS), speech abnormalities are common and can be detected…
Self-limited focal epilepsy and childhood apraxia of speech with WAC pathogenic variants
Highlights • Four children with heterozygous WAC pathogenic variants and epilepsy are described. • All children had global developmental impairment with language most severely affected. • Two children had childhood apraxia of speech and 2 had autism…
Speech, language and oromotor skills in patients with polymicrogyria
Objective: To determine whether specific speech, language and oromotor profiles are associated with different patterns of polymicrogyria (PMG), we assessed 52 patients with PMG using a battery of standardised tests and correlated findings with topography and…
Recording speech: Methods and formats – Manual of Clinical Phonetics
Hardware selection is a an important and often overlooked aspect of speech research
Redenlab chosen for new multinational natural history study in Dentatorubral-pallidoluysian atrophy (DRPLA)
Redenlab Inc, the speech neuroscience company delivering insights in communication testing, announces that it has been selected by USA and UK based charities to support their upcoming natural history study in Dentatorubral-pallidoluysian atrophy (DRPLA). Conducted…
Redenlab selected to support a pivotal Phase 2a gene therapy trial in Friedreich ataxia
Redenlab Inc, the speech neuroscience company delivering insights in speech and language testing, announces that it has been selected by medium sized USA pharmaceutical company to support their upcoming gene therapy study in Friedreich ataxia (FA). Conducted across 5 sites in 3 countries over 2 years, the Phase 2a study will investigate the safety, tolerability and efficacy of gene therapy on adolescents with FA. For the study, Redenlab will provide advanced speech recording and analysis solutions.